1-Alaninechlamydocin

Name: 1-Alaninechlamydocin
Brand: TargetMol
SKU: T36797
Rating: 4.5 (1 reviews)

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货号 T36797Cas号 141446-96-0

1-Alaninechalmydocin is a fungal metabolite originally isolated from a Great Lakes-derived Tolypocladium sp. and an inhibitor of histone deacetylases (HDACs). It reduces total HDAC activity in HeLa cell lysates in a concentration-dependent manner. 1-Alaninechlamydocin reduces proliferation of MIA PaCa-2, PANC-1, and hTERT-HPNE cells (GI50s = 5.3, 14, and 2.0 nM, respectively).

1-Alaninechlamydocin

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货号 T36797Cas号 141446-96-0

规格	价格	库存	数量
5 mg	¥ 46,000	待询

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生物活性

产品描述	1-Alaninechalmydocin is a fungal metabolite originally isolated from a Great Lakes-derived Tolypocladium sp. and an inhibitor of histone deacetylases (HDACs). It reduces total HDAC activity in HeLa cell lysates in a concentration-dependent manner. 1-Alaninechlamydocin reduces proliferation of MIA PaCa-2, PANC-1, and hTERT-HPNE cells (GI50s = 5.3, 14, and 2.0 nM, respectively).
靶点活性	HDAC:6.4 nM (IC50)

化学信息

分子量	512.607
分子式	C₂₇H₃₆N₄O₆
CAS No.	141446-96-0
Smiles	[H][C@]12CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](CCCCCC(=O)[C@@H]1CO1)NC2=O

储存&溶解度

存储	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度信息	DMSO: Soluble