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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GORASP2 Polyclonal Antibody

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货号 TMAB-06640

Anti-GORASP2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GORASP2。Anti-GORASP2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-GORASP2 Polyclonal Antibody

Anti-GORASP2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06640

Anti-GORASP2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GORASP2。Anti-GORASP2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

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产品描述
Anti-GORASP2 Polyclonal Antibody is a Rabbit antibody targeting GORASP2. Anti-GORASP2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep,Xenopus laevis)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Golgi apparatus membrane.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The Golgi apparatus is a highly complex organelle comprised of a stack of cisternal membranes on the secretory pathway from the ER to the cell surface. The structure is maintained by an exoskeleton or Golgi matrix constructed from a family of coiled-coil protein, the golgins and other peripheral membrane components such as GRASP55 and GRASP65 (1). GRASP55 (Golgi reassembly stacking protien or p59) is a component of the Golgi stacking machinery. GRASP55 is highly homologous to GRASP65 and contains two PDZ domains. GRASP55 is myristoylated and palmitoylated. Unlike GRASP65, GRASP55 does not have detectable binding with the vesicle docking protein GM130 and is located on the medial-Golgi rather than cis-Golgi. Both GRASP55 and GRASP65 function in the stacking of Golgi Cisternae (2,3). The novel coiled-coil protein golgin 45 interacts with GRASP55 and the GTP form of Rab 2, suggesting that GRASP55 and golgin 45 form a Rab 2 effector complex on medial-Golgi essential for normal protein transport and Golgi structure (4). ERK2 directly phosphorylates GRASP55, which is phosphorylated in mitotic cells, suggesting that mitogen-activated protein kinase kinase (MKK)/ERK pathway phosphorylates the Golgi during mitosis (5).
抗原信息
免疫原
KLH conjugated synthetic peptide: human GORASP2/Golgi phosphoprotein 6/GRASP55
抗原种属
Human
基因名称
GORASP2
基因ID
26003
蛋白名称
Golgi reassembly-stacking protein 2
Uniprot ID
Q9H8Y8
功能
May be involved in assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA.
化学信息
分子量Theoretical: 47 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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