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Anti-KLK10 Polyclonal Antibody

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Anti-KLK10 Polyclonal Antibody
产品编号 TMAB-01029

Anti-KLK10 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KLK10。Anti-KLK10 Polyclonal Antibody 可用于 WB。

Anti-KLK10 Polyclonal Antibody

Anti-KLK10 Polyclonal Antibody

Rating icon 还可以
Anti-KLK10 Polyclonal Antibody
产品编号 TMAB-01029

Anti-KLK10 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KLK10。Anti-KLK10 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-KLK10 Polyclonal Antibody is a Rabbit antibody targeting KLK10. Anti-KLK10 Polyclonal Antibody can be used in WB.
Ig Type
IgG
交叉反应
Human (predicted:Mouse,Rat,Cow)
验证活性
1. Sample:
MCF-7 (Human) Cell Lysate at 30 μg
Primary: Anti-NES/Kallikrein 10 (TMAB-01029) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 31 kDa
Observed band size: 31 kDa
2. Sample:
DU145 (Human) Cell Lysate at 30 μg
Primary: Anti-NES/Kallikrein 10 (TMAB-01029) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 31 kDa
Observed band size: 31 kDa
应用
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景Kallikrein 10 is a trypsin-like serine proteinase. Originally described from a subtractive library looking for genes that were down-regulated in breast cancer, kallikrein 10 was thought to be epithelial cell specific. Kallikrein 10 is reported to be up regulated in pancreatic cancer and ovarian cancer, but down regulated in testicular cancer and breast cancer, perhaps due to differential hormonal regulation, or tissue specificities. Breast cancer patients that had elevated kallikrein 10 had a worse prognosis, leading to speculation that kallikrein 10 might be protective in breast cancer, similar to the argument put forth for kallikrein 3 in prostate cancer. Kallikrein 10 is found in high levels in the pancreas and in lower levels in the tonsils, esophagus, skin, brain, testis and ovary. Biological fluids (breast milk, serum, seminal plasma, urine) contain kallikrein 10, the highest levels found in milk. The cerebral spinal fluid (CSF) contains Kallikrein 10, and was reported to be elevated in patients with Alzheimer’s disease. Endogenous inhibitors include kallistatin, protein-C inhibitor and 1-proteinase inhibitor, although Kallikrein 10 can be found complexed to a number of different proteinase inhibitors.
抗原信息
免疫原
KLH conjugated synthetic peptide: human KLK10
抗原种属
Human
基因ID
Uniprot ID
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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