Name: CEM114
Brand: TargetMol
SKU: T39810
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

25 mg

¥ 10,600

待询

生物活性

产品描述	CEM114 is a potent chemical compound known as a chemical epigenetic modifier (CEM). It functions by employing CRISPR-Cas9 systems to harness endogenous chromatin machinery, thereby exerting its epigenetic modifying effects.
体外活性	CEM114 (200 nM; 48 hours) treatment significantly activates the Green Fluorescent Protein (GFP) signal, suggesting that excess FK506 is able to outcompete CEM114 from the FKBP binding site[1]. Cell Viability Assay[1]Cell Line: HEK 293T cells Concentration: 200 nM Incubation Time: 48 hours Result: Significantly activated the GFP signal.

化学信息

分子量	1613.0
分子式	C₈₄H₁₂₂FN₉O₁₉S
CAS No.	2279062-54-1
Smiles	[H][C@@]12CCCCN1C(=O)C(=O)[C@]1(O)O[C@@]([H])([C@H](C[C@H]1C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CCCSCCC(=O)NCCOCCOCCOCCn1cc(COc3ccc(CCc4nc5cc(ccc5n4CCN4CCOCC4)-c4c(C)noc4C)cc3F)nn1)C(=O)C[C@H](O)[C@@H](C)[C@H](OC2=O)C(\C)=C\[C@@H]1CC[C@@H](O)[C@@H](C1)OC)OC \|t:30\|