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Anti-Serpin A5 Antibody (7V96)

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产品编号 TMAY-00595

Anti-Serpin A5 Antibody (7V96) 是一种 Mouse 抗体,靶向 Serpin A5。Anti-Serpin A5 Antibody (7V96) 可用于 ELISA。

Anti-Serpin A5 Antibody (7V96)

Anti-Serpin A5 Antibody (7V96)

Rating icon 还可以
产品编号 TMAY-00595

Anti-Serpin A5 Antibody (7V96) 是一种 Mouse 抗体,靶向 Serpin A5。Anti-Serpin A5 Antibody (7V96) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-Serpin A5 Antibody (7V96) is a Mouse antibody targeting Serpin A5. Anti-Serpin A5 Antibody (7V96) can be used in ELISA.
Ig Type
Monoclonal Mouse IgG1
克隆号
7V96
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant human SerpinA5 (rhSerpinA5; Met1-Pro406NP_000615.3). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Serpin A5, also well known as protein C inhibitor (PCI), is a member of the human serpin superfamily that consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent inhibitor of the protein C anticoagulant pathway at the levels of both zymogen activation and enzyme inhibition, serpinA5 additionally inhibits a variety of serine protease including thrombin, factor Xa, several kallekreins and acrosin, and plays a role in the processes of blood coagulation and fertilization. Serpin A5 also inhibits urinary plasminogen activator (uPA), a mediator of tumor cell invasion, and regulates tumor growth and metastasis by inhibiting angiogenesis. Furthermore, recent studies have identified PCI as a potent and direct inhibitor of activated HGFA (hepatocyte growth factor activator), suggesting a novel function in the regulation of tissue repair and regeneration. Similar to serpins C1 and D1, the thrombin inhibitory activity of serpinA5 is enhanced by heparin.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human SerpinA5 protein
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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