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Anti-GIT1 Antibody (6A39)

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Anti-GIT1 Antibody (6A39)
产品编号 TMAC-01662
别名 GRK-interacting protein 1, GRK interacting protein 1, GIT1_HUMAN, GIT 1, G protein-coupled receptor kinase-interactor 1, G protein coupled receptor kinase interactor 1, G protein coupled receptor kinase interacting ArfGAP 1, Cool-associated and tyrosine-phosphorylated protein 1, Cool associated and tyrosine phosphorylated protein 1, CAT-1, CaT1, CAT 1, ARF GTPase-activating protein GIT1, ARF GTPase activating protein GIT1, ARF GAP GIT1

Anti-GIT1 Antibody (6A39) 是一种 Rabbit 抗体,靶向 GIT1。Anti-GIT1 Antibody (6A39) 可用于 WB,IHC,FCM。

Anti-GIT1 Antibody (6A39)

Anti-GIT1 Antibody (6A39)

Rating icon 还可以
Anti-GIT1 Antibody (6A39)
产品编号 TMAC-01662 别名 GRK-interacting protein 1, GRK interacting protein 1, GIT1_HUMAN, GIT 1, G protein-coupled receptor kinase-interactor 1, G protein coupled receptor kinase interactor 1, G protein coupled receptor kinase interacting ArfGAP 1, Cool-associated and tyrosine-phosphorylated protein 1, Cool associated and tyrosine phosphorylated protein 1, CAT-1, CaT1, CAT 1, ARF GTPase-activating protein GIT1, ARF GTPase activating protein GIT1, ARF GAP GIT1

Anti-GIT1 Antibody (6A39) 是一种 Rabbit 抗体,靶向 GIT1。Anti-GIT1 Antibody (6A39) 可用于 WB,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-GIT1 Antibody (6A39) is a Rabbit antibody targeting GIT1. Anti-GIT1 Antibody (6A39) can be used in WB,IHC,FCM.
别名GRK-interacting protein 1, GRK interacting protein 1, GIT1_HUMAN, GIT 1, G protein-coupled receptor kinase-interactor 1, G protein coupled receptor kinase interactor 1, G protein coupled receptor kinase interacting ArfGAP 1, Cool-associated and tyrosine-phosphorylated protein 1, Cool associated and tyrosine phosphorylated protein 1, CAT-1, CaT1, CAT 1, ARF GTPase-activating protein GIT1, ARF GTPase activating protein GIT1, ARF GAP GIT1
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of GIT1 on A549 cell using anti-GIT1 antibody at 1/500 dilution.
2. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-GIT1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-GIT1 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse fallopian tubes tissue using anti-GIT1 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-GIT1 antibody. Counter stained with hematoxylin.
6. Flow cytometric analysis of A549 cells with GIT1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
应用
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade. GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking. GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 85 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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