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Anti-Phospho-AS160 (Ser318) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-AS160 (Ser318)。Anti-Phospho-AS160 (Ser318) Polyclonal Antibody 可用于 WB。
Anti-Phospho-AS160 (Ser318) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-AS160 (Ser318)。Anti-Phospho-AS160 (Ser318) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,245 | 5日内发货 |
产品描述 | Anti-Phospho-AS160 (Ser318) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AS160 (Ser318). Anti-Phospho-AS160 (Ser318) Polyclonal Antibody can be used in WB. |
别名 | p-AS160 (Ser318), p-AS160 (S318), AS160 (p-Ser318), AS160 (p-S318) |
Ig Type | IgG |
交叉反应 | Human |
应用 | |
推荐剂量 | WB: 1:1000-2000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
性状 | Liquid |
缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
研究背景 | TBC1 domain family member 4(TBC1D4) Homo sapiens This gene is a member of the Tre-2/BUB2/CDC16 domain family. The protein encoded by this gene is a Rab-GTPase-activating protein, and contains two phopshotyrosine-binding domains (PTB1 and PTB2), a calmodulin-binding domain (CBD), a Rab-GTPase domain, and multiple AKT phosphomotifs. This protein is thought to play an important role in glucose homeostasis by regulating the insulin-dependent trafficking of the glucose transporter 4 (GLUT4), important for removing glucose from the bloodstream into skeletal muscle and fat tissues. Reduced expression of this gene results in an increase in GLUT4 levels at the plasma membrane, suggesting that this protein is important in intracellular retention of GLUT4 under basal conditions. When exposed to insulin, this protein is phosphorylated, dissociates from GLUT4 vesicles, resulting in increased GLUT4 at the cell surface, and enhanced glucose transport. Ph |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human AS160 around the phosphorylation site of Ser318 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 145 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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