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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-HMGN2/HMG17 Polyclonal Antibody

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货号 TMAB-07190

Anti-HMGN2/HMG17 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HMGN2/HMG17。Anti-HMGN2/HMG17 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-HMGN2/HMG17 Polyclonal Antibody

Anti-HMGN2/HMG17 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-07190

Anti-HMGN2/HMG17 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HMGN2/HMG17。Anti-HMGN2/HMG17 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-HMGN2/HMG17 Polyclonal Antibody is a Rabbit antibody targeting HMGN2/HMG17. Anti-HMGN2/HMG17 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Pig,Cow,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Cytoplasmic enrichment upon phosphorylation.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The high-mobility group (HMG) proteins 14 and 17 are abundant chromosomal proteins that bind to nucleosomes and enhance transcription (1–5). HMG-14 and HMG-17 also function as architectural elements, which alter the structure of the chromatin fiber and enhance transcription from chromatin templates (1–3,5). HMG-14/17 proteins modify the nucleosomal organization of the 30 nm chromatin fiber and mediate the unfolding of the higher order chromatin structure thereby facilitating access to the underlying DNA sequence (1–3). Clustering of architectural elements, such as HMG proteins and linker histone subtypes into distinct domains, may lead to structural and functional heterogeneity along the chromatin fiber (1–3). In addition, HMG-14 and HMG-17 have been identified as constitutive components of mouse oocyte and embryonic chromatin that establish a link between the structure of embryonic chromatin and the normal progression of embryonic development (2).
抗原信息
免疫原
KLH conjugated synthetic peptide: human HMGN2/HMG17
抗原种属
Human
基因名称
HMGN2
基因ID
3151
蛋白名称
Non-histone chromosomal protein HMG-17
Uniprot ID
P05204
功能
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation.
化学信息
分子量Theoretical: 9.2 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
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