Name: Anti-CDH6/K-Cadherin Antibody
Brand: TargetMol
SKU: T9901A-823
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

1 mg

待询

5 mg

待询

生物活性

产品描述	Anti-CDH6/K-Cadherin Antibody is a highly specialized monoclonal antibody target the human cadherin-6 protein, which is a type II classical cadherin primarily expressed in the kidney and various malignant tissues, inhibition of calcium-dependent cell-cell adhesion across various preclinical experimental models to modulate tumor cell invasion and metastatic potential.
体外活性	在利用 OVCAR-3 卵巢癌细胞进行的细胞毒性实验中，Anti-CDH6/K-Cadherin Antibody (HKT288 ADC) 展示了强效的抗原特异性杀伤活性，IC50 值处于低纳摩尔范围 [1]。
体内活性	在人卵巢癌和肾癌异种移植模型中，通过全身给药方式给予 Anti-CDH6/K-Cadherin Antibody (HKT288 ADC)，实验结果显示肿瘤显著退缩并产生了持久的抗肿瘤响应 [1]。
别名	抗CDH6/K-Cadherin抗体, HKT288 antibody
反应种属	Human
应用	ELISA FACS Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型

IgG1

偶联与修饰

偶联	Unconjugated

抗原信息

Uniprot ID	P55285
靶点	CDH6/K-Cadherin

储存&溶解度

存储

Anti-CDH6/K-Cadherin Antibody