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Anti-FTCD Antibody (8U835)

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Anti-FTCD Antibody (8U835)
产品编号 TMAC-00031
别名 LCHC1, formimidoyltransferase cyclodeaminase

Anti-FTCD Antibody (8U835) 是一种 Rabbit 抗体,靶向 FTCD。Anti-FTCD Antibody (8U835) 可用于 WB,IHC,FCM。

Anti-FTCD Antibody (8U835)

Anti-FTCD Antibody (8U835)

Rating icon 还可以
Anti-FTCD Antibody (8U835)
产品编号 TMAC-00031 别名 LCHC1, formimidoyltransferase cyclodeaminase

Anti-FTCD Antibody (8U835) 是一种 Rabbit 抗体,靶向 FTCD。Anti-FTCD Antibody (8U835) 可用于 WB,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-FTCD Antibody (8U835) is a Rabbit antibody targeting FTCD. Anti-FTCD Antibody (8U835) can be used in WB,IHC,FCM.
别名LCHC1, formimidoyltransferase cyclodeaminase
Ig Type
IgG
克隆号
8U835
交叉反应
Human
验证活性
1. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-58K Golgi protein antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-58K Golgi protein antibody. Counter stained with hematoxylin.
3. Flow cytometric analysis of HepG2 cells with 58K Golgi protein antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景58K protein antibodies are excellent for use as markers for the Golgi complex. The 58K protein has been identified as being FTCD, a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Defects in FTCD are the cause of glutamate formiminotransferase deficiency [also known as formiminoglutamicaciduria (FIGLU-uria)], an autosomal recessive disorder. Features of a severe phenotype include elevated levels of formiminoglutamate (FIGLU) in the urine in response to histidine administration, megaloblastic anemia and mental retardation. Features of a mild phenotype include high urinary excretion of FIGLU in the absence of histidine administration, mild developmental delay and no hematological abnormalities.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 59 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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