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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-MRP1/ABCC1 Polyclonal Antibody

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货号 TMAB-08995

Anti-MRP1/ABCC1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MRP1/ABCC1。Anti-MRP1/ABCC1 Polyclonal Antibody 可用于 WB。

Anti-MRP1/ABCC1 Polyclonal Antibody

Anti-MRP1/ABCC1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08995

Anti-MRP1/ABCC1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MRP1/ABCC1。Anti-MRP1/ABCC1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-MRP1/ABCC1 Polyclonal Antibody is a Rabbit antibody targeting MRP1/ABCC1. Anti-MRP1/ABCC1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Cow,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
组织特异性Lung, testis and peripheral blood mononuclear cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]
抗原信息
免疫原
KLH conjugated synthetic peptide: human MRP1/ABCC1
抗原种属
Human
基因名称
ABCC1
基因ID
4363
蛋白名称
Multidrug resistance-associated protein 1
Uniprot ID
P33527
功能
Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
化学信息
分子量Theoretical: 170 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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