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别名 Geminin
Anti-GMNN Antibody (6Z839) 是一种抗体,靶向 GMNN。Anti-GMNN Antibody (6Z839) 可用于 ELISA,IF。
Anti-GMNN Antibody (6Z839) 是一种抗体,靶向 GMNN。Anti-GMNN Antibody (6Z839) 可用于 ELISA,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,190 | 5日内发货 |
| 产品描述 | Anti-GMNN Antibody (6Z839) is an antibody targeting GMNN. Anti-GMNN Antibody (6Z839) can be used in ELISA,IF. |
| 别名 | Geminin |
| Ig Type | Rabbit IgG |
| 克隆号 | 6Z839 |
| 交叉反应 | Human |
| 验证活性 | Immunofluorescence staining of Hela Cells with TMAH-00498 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L). |
| 应用 | ELISAIF |
| 推荐剂量 | IF:1:20-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cytoplasm. Nucleus. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle. Inhibits histone acetyltransferase activity of KAT7/HBO1 in a CDT1-dependent manner, inhibiting histone H4 acetylation and DNA replication licensing. Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human Geminin |
| 抗原种属 | Human |
| 基因名称 | GMNN |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Epigenetics and Nuclear Signaling, Cancer |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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