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Anti-GMNN Antibody (6Z839)

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Anti-GMNN Antibody (6Z839)
产品编号 TMAH-00498
别名 Geminin

Anti-GMNN Antibody (6Z839) 是一种抗体,靶向 GMNN。Anti-GMNN Antibody (6Z839) 可用于 ELISA, IF。

Anti-GMNN Antibody (6Z839)

Anti-GMNN Antibody (6Z839)

Rating icon 还可以
Anti-GMNN Antibody (6Z839)
产品编号 TMAH-00498 别名 Geminin

Anti-GMNN Antibody (6Z839) 是一种抗体,靶向 GMNN。Anti-GMNN Antibody (6Z839) 可用于 ELISA, IF。

规格价格库存数量
50 μL
¥ 1,305
5日内发货
100 μL
¥ 2,190
5日内发货
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产品介绍

生物活性
产品描述
Anti-GMNN Antibody (6Z839) is an antibody targeting GMNN. Anti-GMNN Antibody (6Z839) can be used in ELISA, IF.
别名Geminin
Ig Type
Rabbit IgG
克隆号
6Z839
交叉反应
Human
验证活性
Immunofluorescence staining of Hela Cells with TMAH-00498 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).
应用
推荐剂量
IF:1:20-1:200.
抗体种类
Monoclonal
亚细胞定位Cytoplasm. Nucleus.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle. Inhibits histone acetyltransferase activity of KAT7/HBO1 in a CDT1-dependent manner, inhibiting histone H4 acetylation and DNA replication licensing. Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human Geminin
抗原种属
Human
基因ID
Uniprot ID
研究领域
Epigenetics and Nuclear Signaling, Cancer
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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