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Anti-AGTR2 Antibody (5P814)
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产品编号 TMAC-00207
别名 Type 2 angiotensin II receptor, MRX88, MRX 88, ATGR2, ATGR 2, AT2R2, AT2, AT 2, Angiotensin receptor 2, Angiotensin II type-2 receptor, Angiotensin II Type 2, angiotensin II receptor type 2, AGTR2, AGTR 2
Anti-AGTR2 Antibody (5P814) 是一种 Rabbit 抗体，靶向 AGTR2。Anti-AGTR2 Antibody (5P814) 可用于 WB,IP。
Anti-AGTR2 Antibody (5P814)
Anti-AGTR2 Antibody (5P814)
还可以产品编号 TMAC-00207 别名 Type 2 angiotensin II receptor, MRX88, MRX 88, ATGR2, ATGR 2, AT2R2, AT2, AT 2, Angiotensin receptor 2, Angiotensin II type-2 receptor, Angiotensin II Type 2, angiotensin II receptor type 2, AGTR2, AGTR 2
Anti-AGTR2 Antibody (5P814) 是一种 Rabbit 抗体，靶向 AGTR2。Anti-AGTR2 Antibody (5P814) 可用于 WB,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,495 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
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偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-AGTR2 Antibody (5P814) is a Rabbit antibody targeting AGTR2. Anti-AGTR2 Antibody (5P814) can be used in WB,IP. |
| 别名 | Type 2 angiotensin II receptor, MRX88, MRX 88, ATGR2, ATGR 2, AT2R2, AT2, AT 2, Angiotensin receptor 2, Angiotensin II type-2 receptor, Angiotensin II Type 2, angiotensin II receptor type 2, AGTR2, AGTR 2 |
| Ig Type | IgG |
| 克隆号 | 5P814 |
| 交叉反应 | Human,Mouse,Rat |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Angiotensin II (Ang II) is an important physiological effector of blood pressure and volume regulation through vasoconstriction, aldosterone release, sodium uptake and thirst stimulation. Although Ang II interacts with two types of cell surface receptors, AT1 and AT2, most of the major cardiovascular effects seem to be mediated through AT1. Molecular cloning of the AT1 protein has shown it to be a member of the G protein-associated seven transmembrane protein receptor family. Ang II treatment of cells results in activation of several signal transduction pathways as evidenced by tyrosine phosphorylation of several proteins and induction of others. PLCγ is phosphorylated after 30 seconds of treatment with Angiotensin II, indicating this as an early signal transduction event. Ang II treatment also stimulates phosphorylation of Shc, FAK and MAP kinases, and induces MKP-1, indicating stimulation of growth factor pathways. Ang II stimulation through AT1 has been shown to activate the JAK/Stat pathway involving a direct interaction between JAK2 and AT1 as demonstrated by coimmunoprecipitation. The AT1 receptor has no cytoplasmic kinase domain, but is able to function as a substrate for Src kinases and has several putative phosphorylation sites. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 41 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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