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顶部生物活性储存和溶解信息计算器

Anti-Phospho-PDGFRB (Y740) Antibody (1I961)

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Anti-Phospho-PDGFRB (Y740) Antibody (1I961)
产品编号 TMAC-03115
别名 p-PDGFRB (Y740), PDGFRB (p-Y740)

Anti-Phospho-PDGFRB (Y740) Antibody (1I961) 是一种 Rabbit 抗体，靶向 Phospho-PDGFRB (Y740)。Anti-Phospho-PDGFRB (Y740) Antibody (1I961) 可用于 WB,ICC/IF。

Anti-Phospho-PDGFRB (Y740) Antibody (1I961)

Anti-Phospho-PDGFRB (Y740) Antibody (1I961)

Rating icon 还可以
Anti-Phospho-PDGFRB (Y740) Antibody (1I961)
产品编号 TMAC-03115 别名 p-PDGFRB (Y740), PDGFRB (p-Y740)

Anti-Phospho-PDGFRB (Y740) Antibody (1I961) 是一种 Rabbit 抗体，靶向 Phospho-PDGFRB (Y740)。Anti-Phospho-PDGFRB (Y740) Antibody (1I961) 可用于 WB,ICC/IF。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-PDGFRB (Y740) Antibody (1I961) is a Rabbit antibody targeting Phospho-PDGFRB (Y740). Anti-Phospho-PDGFRB (Y740) Antibody (1I961) can be used in WB,ICC/IF.
别名p-PDGFRB (Y740), PDGFRB (p-Y740)
Ig Type
IgG
交叉反应
Mouse,Rat
验证活性
1. ICC staining PDGF Receptor beta(phospho Y740) in C2C12 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
2. ICC staining PDGF Receptor beta(phospho Y740) in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC/IF
推荐剂量
WB: 1:1000; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Platelet Derived Growth Factor (PDGF) is a mitogen for mesenchyme- and glia-derived cells. PDGF consists of two chains, A and B, which dimerize to form functionally distinct isoforms, PDGF-AA, PDGF-AB, and PDGF-BB. These three isoforms bind with different affinities to two receptor types, a and b, which are endowed with protein tyrosine kinase domains and undergo either homo- or heterodimerization as a consequence of ligand binding. Ligand stimulation of PDGFR-b leads to autophosphorylation at Tyr-857, which is the major autophosphorylation site, and Tyr-751, which is the major in vitro phosphorylation site. Autophosphorylation of Tyr-751, which lies in the kinase insert region, is required for binding of phosphatidylinositol-3 kinase to the receptor. These auto-phosphorylation events largely contribute to signal transduction through the PDGF receptor.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human PDGF Receptor beta around the phosphorylation site of Tyr740
抗原种属
human
Uniprot ID
P05622
化学信息
分子量Theoretical: 190 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pPDGFRB (Y740)PDGFRB (pY740)PDGFRB (phospho-Y740)

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