Anti-CD47 Antibody (8K78)

Name: Anti-CD47 Antibody (8K78)
Brand: TargetMol
SKU: TMAY-03581
Rating: 4.5 (1 reviews)

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产品编号 TMAY-03581

别名 OA3, MER6, IAP, CD47 molecule

Anti-CD47 Antibody (8K78) 是一种 Rabbit 抗体，靶向 CD47。Anti-CD47 Antibody (8K78) 可用于 WB,ELISA,IP。

Anti-CD47 Antibody (8K78)

还可以

产品编号 TMAY-03581 别名 OA3, MER6, IAP, CD47 molecule

Anti-CD47 Antibody (8K78) 是一种 Rabbit 抗体，靶向 CD47。Anti-CD47 Antibody (8K78) 可用于 WB,ELISA,IP。

规格	价格	库存	数量
100 μL	¥ 1,679	5日内发货

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生物活性

产品描述	Anti-CD47 Antibody (8K78) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (8K78) can be used in WB,ELISA,IP.
别名	OA3, MER6, IAP, CD47 molecule
Ig Type	Monoclonal Rabbit IgG
克隆号	8K78
交叉反应	Mouse
验证活性	1. Anti-CD47 rabbit polyclonal antibody at 1:500 dilution. -Lane A: Mouse brain tissue lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:35 kDa. 2. mCD47 was immunoprecipitated using: -Lane A:0.5 mg Mouse brain Whole Cell Lysate. -4 µL anti-mCD47 rabbit monoclonal antibody and 60 μg of Immunomagnetic beads Protein A/G. -Primary antibody: -Anti-mCD47 rabbit monoclonal antibody, at 1:100 dilution. -Secondary antibody: -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size: 40 kDa. -Observed band size:40 kDa
应用	WB,ELISA,IP
推荐剂量	WB: 1:500-1:2000; ELISA: 1:5000-1:10000; IP: 1-5 μL/mg of lysate
抗体种类	Monoclonal
宿主来源	Rabbit
构建方式	This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD47 (rM CD47; TMPY-04810; Q61735-1; Met1-Lys140).
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Mouse CD47 Protein (TMPY-04810)
抗原种属	Mouse
研究领域	Cancer Drug Targets

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.