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Anti-Hippocalcin Polyclonal Antibody

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货号 TMAB-07049

Anti-Hippocalcin Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Hippocalcin。Anti-Hippocalcin Polyclonal Antibody 可用于 WB。

Anti-Hippocalcin Polyclonal Antibody

Anti-Hippocalcin Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-07049

Anti-Hippocalcin Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Hippocalcin。Anti-Hippocalcin Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-Hippocalcin Polyclonal Antibody is a Rabbit antibody targeting Hippocalcin. Anti-Hippocalcin Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Cow,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Brain specific.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Hippocalcin is a neuron-specific calcium-binding protein found primarily in the plasma membrane of brain and retinal tissue, with increased expression observed in hippocampal pyramidal cells. Through its calcium-dependent signal regulation, hippocalcin can both inhibit rhodopsin kinase and increase phospholipase D2 expression. In order to regulate kinase and phospholipase activity, hippocalcin must bind to the plasma membrane where it can then bind two calcium ions for use in signal regulation. The hippocalcin protein is highly conserved in mouse, rat and human tissue and has a suggested role in neural plasticity and associative memory by contributing to the survival of neurons during aging. The loss of hippocalcin expression is thought to contribute to age-related impairment of post-synaptic functions related to neuronal degradation.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Hippocalcin
抗原种属
Human
基因名称
HPCA
基因ID
蛋白名称
Neuron-specific calcium-binding protein hippocalcin
Uniprot ID
功能
May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds two calcium ions.
化学信息
分子量Theoretical: 22 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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