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Anti-Hippocalcin Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Hippocalcin。Anti-Hippocalcin Polyclonal Antibody 可用于 WB。
Anti-Hippocalcin Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Hippocalcin。Anti-Hippocalcin Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-Hippocalcin Polyclonal Antibody is a Rabbit antibody targeting Hippocalcin. Anti-Hippocalcin Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Mouse,Rat (predicted:Human,Chicken,Cow,Rabbit) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 组织特异性 | Brain specific. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Hippocalcin is a neuron-specific calcium-binding protein found primarily in the plasma membrane of brain and retinal tissue, with increased expression observed in hippocampal pyramidal cells. Through its calcium-dependent signal regulation, hippocalcin can both inhibit rhodopsin kinase and increase phospholipase D2 expression. In order to regulate kinase and phospholipase activity, hippocalcin must bind to the plasma membrane where it can then bind two calcium ions for use in signal regulation. The hippocalcin protein is highly conserved in mouse, rat and human tissue and has a suggested role in neural plasticity and associative memory by contributing to the survival of neurons during aging. The loss of hippocalcin expression is thought to contribute to age-related impairment of post-synaptic functions related to neuronal degradation. |
| 免疫原 | KLH conjugated synthetic peptide: human Hippocalcin |
| 抗原种属 | Human |
| 基因名称 | HPCA |
| 基因ID | |
| 蛋白名称 | Neuron-specific calcium-binding protein hippocalcin |
| Uniprot ID | |
| 功能 | May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds two calcium ions. |
| 分子量 | Theoretical: 22 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |