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Anti-NQO1 Antibody (2T646)
还可以产品编号 TMAY-02207
别名 QR1, NMORI, NMOR1, NAD(P)H dehydrogenase, quinone 1, DTD, DIA4, DHQU
Anti-NQO1 Antibody (2T646) 是一种 Rabbit 抗体，靶向 NQO1。Anti-NQO1 Antibody (2T646) 可用于 WB。
Anti-NQO1 Antibody (2T646)
Anti-NQO1 Antibody (2T646)
还可以产品编号 TMAY-02207 别名 QR1, NMORI, NMOR1, NAD(P)H dehydrogenase, quinone 1, DTD, DIA4, DHQU
Anti-NQO1 Antibody (2T646) 是一种 Rabbit 抗体，靶向 NQO1。Anti-NQO1 Antibody (2T646) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,289 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-NQO1 Antibody (2T646) is a Rabbit antibody targeting NQO1. Anti-NQO1 Antibody (2T646) can be used in WB. |
| 别名 | QR1, NMORI, NMOR1, NAD(P)H dehydrogenase, quinone 1, DTD, DIA4, DHQU |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 2T646 |
| 交叉反应 | Human |
| 验证活性 | Anti-NQO1 rabbit monoclonal antibody at 1:500 dilution. -Lane A: A549 Whole Cell Lysate. -Lane B: MCF7 Whole Cell Lysate. -Lane C: Raji Whole Cell Lysate. -Lane D: HepG2 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:31 kDa. -Observed band size:31 kDa |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human NQO1 (rh NQO1; TMPY-03407; P15559-1; Met1-Lys274). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of NQO1 has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Recent pharmacological research suggests the feasibility of genotype-directed redox chemotherapeutic intervention targeting NQO1 breast cancer, a common missense genotype encoding a functionally impaired NQO1 protein. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human NQO1 Protein (TMPY-03407) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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