(R)-Dinotefuran ((R)-MTI-446), a neonicotinoid pesticide, demonstrates insecticidal activities 1.7-2.4 times more effective against typical sucking pests like Aphis gossypii and Apolygus lucorum when compared to its racemic mixtures, by targeting nicotinic acetylcholine receptors. Additionally, (R)-Dinotefuran is effective in managing these pests while posing a reduced risk to honeybees [1].