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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ACAN Polyclonal Antibody

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货号 TMAB-02188

Anti-ACAN Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ACAN。Anti-ACAN Polyclonal Antibody 可用于 WB,ELISA。

Anti-ACAN Polyclonal Antibody

Anti-ACAN Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-02188

Anti-ACAN Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ACAN。Anti-ACAN Polyclonal Antibody 可用于 WB,ELISA。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-ACAN Polyclonal Antibody is a Rabbit antibody targeting ACAN. Anti-ACAN Polyclonal Antibody can be used in WB,ELISA.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
应用WBELISA
推荐剂量
WB: 1:500-2000; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted, extracellular space, extracellular matrix.
组织特异性Restricted to cartilages.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Aggrecan is a member of a family of large, aggregating proteoglycans (also including versican, brevican and neurocan) which is found in articular cartilage. Aggrecan is composed of three major domains: G1, G2, and G3. Between the G1 and G2 domains there is an interglobulin region (IGD). The IGD region is the major site of cleavage by specific proteases like metalloproteinases (MMPs) and aggrecanase. Aggrecan cleavage has been associated with a number of degenerative diseases including rheumatoid arthritis and osteoarthritis. There is evidence that this family of proteoglycans modulates cell adhesion, migration, and axonal outgrowth in the CNS.
抗原信息
免疫原
Recombinant Protein: human ACAN protein
抗原种属
Human
基因名称
ACAN
基因ID
176
蛋白名称
Aggrecan core protein
Uniprot ID
P16112
功能
Aggrecan has been detected in neural precursor cells (neurospheres; Kabos et al, 2004) During differentiation, neurospheres downregulate Chondroitin sulfate proteoglycans (CSPGs). Proliferating neural precursors synthesize lecticans, including aggrecan, which are downregulated with differentiation; suggesting a link between CSPGs and CNS precursor biology.
化学信息
分子量Theoretical: 222 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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