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Anti-TBR1 Antibody (9V334)

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货号 TMAB-13402

Anti-TBR1 Antibody (9V334) 是一种 Rabbit 抗体，靶向 TBR1。Anti-TBR1 Antibody (9V334) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-TBR1 Antibody (9V334)

Anti-TBR1 Antibody (9V334)

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Rating icon 还可以
货号 TMAB-13402

Anti-TBR1 Antibody (9V334) 是一种 Rabbit 抗体，靶向 TBR1。Anti-TBR1 Antibody (9V334) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-TBR1 Antibody (9V334) is a Rabbit antibody targeting TBR1. Anti-TBR1 Antibody (9V334) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
9V334
反应种属
Mouse,Rat,Human
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nuclea
组织特异性Brain.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景A novel murine and human gene, TBR-1, encodes a putative transcription factor related to the Brachyrury (T) gene that is expressed only in postmitotic cells. T-brain-1 (TBR-1) mRNA is largely restricted to the cerebral cortex, where, during embryogenesis, it defines different regions that give rise to the palecortex, limbic cortex and neocortex (1-3). TBR-1, Pax-6 and Emx-1 are expressed in the mouse and chicken pallium. The pallio-subpallial boundary lies at the interface between the TBR-1 and Dlx-2 expression domains. Chicken genes homolgous to these mouse genes are expressed in topologically comparable patterns during development, suggesting that mouse and chicken may have similar histogenetic specification processes and field homologies (4). CASK/LIN-2, a membrane-associated guanylate kinase, is required for EGFR localization and signaling. In adult rat brain, CASK is concentrated at neuronal synapses and binds to the cell-surface proteins. CASK can interact with TBR-1, which is involved in forebrain development. CASK enters into the nucleus and binds to a specific DNA sequence (the T-element) in a complex with TBR-1. Thus, CASK acts as a coactivator of TBR-1 to induce transcription of T-element containing genes, including reelin (5).
抗原信息
免疫原
A synthesized peptide: human TBR1
抗原种属
Mouse
基因名称
TBR1
基因ID
21375
蛋白名称
T-box brain protein 1
Uniprot ID
Q64336
功能
Probable transcriptional regulator involved in developmental processes. TBR1 is required for normal brain development.
化学信息
分子量Theoretical: 74 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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