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顶部生物活性储存和溶解信息计算器

Anti-Phospho-c-Fos (Ser374) Polyclonal Antibody

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产品编号 TMAB-10492

Anti-Phospho-c-Fos (Ser374) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-c-Fos (Ser374)。Anti-Phospho-c-Fos (Ser374) Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Phospho-c-Fos (Ser374) Polyclonal Antibody

Anti-Phospho-c-Fos (Ser374) Polyclonal Antibody

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Rating icon 还可以
产品编号 TMAB-10492

Anti-Phospho-c-Fos (Ser374) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-c-Fos (Ser374)。Anti-Phospho-c-Fos (Ser374) Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-c-Fos (Ser374) Polyclonal Antibody is a Rabbit antibody targeting Phospho-c-Fos (Ser374). Anti-Phospho-c-Fos (Ser374) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
交叉反应
Human,Mouse,Rat
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human c-Fos around the phosphorylation site of Ser374
抗原种属
Human
基因名称
FOS
基因ID
2353
蛋白名称
Proto-oncogene c-Fos
Uniprot ID
P01100
功能
Nuclear phosphoprotein which forms a tight butnon-covalently linked complex with the JUN/AP-1 transcriptionfactor. In the heterodimer, FOS and JUN/AP-1 basic regions eachseems to interact with symmetrical DNA half sites. On TGF-betaactivation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at theAP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Hasa critical function in regulating the Has a critical function inregulating the development of cells destined to form and maintainthe skeleton. It is thought to have an important role in signaltransduction, cell proliferation and differentiation.
化学信息
分子量Theoretical: 41 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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