Anti-NGF Antibody (7R395)

Name: Anti-NGF Antibody (7R395)
Brand: TargetMol
SKU: TMAH-00816
Rating: 4.5 (1 reviews)

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产品编号 TMAH-00816

别名 神经生长因子, β-NGF, NGFB, nerve growth factor (β polypeptide), nerve growth factor (beta polypeptide), HSAN5, Beta-NGF

Anti-NGF Antibody (7R395) 是一种抗体，靶向 NGF。Anti-NGF Antibody (7R395) 可用于 ELISA, WB, IHC。

Anti-NGF Antibody (7R395)

还可以

产品编号 TMAH-00816 别名 神经生长因子, β-NGF, NGFB, nerve growth factor (β polypeptide), nerve growth factor (beta polypeptide), HSAN5, Beta-NGF

Anti-NGF Antibody (7R395) 是一种抗体，靶向 NGF。Anti-NGF Antibody (7R395) 可用于 ELISA, WB, IHC。

规格	价格	库存	数量
50 μL	¥ 1,305	5日内发货
100 μL	¥ 2,195	5日内发货

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产品描述	Anti-NGF Antibody (7R395) is an antibody targeting NGF. Anti-NGF Antibody (7R395) can be used in ELISA, WB, IHC.
别名	神经生长因子, β-NGF, NGFB, nerve growth factor (β polypeptide), nerve growth factor (beta polypeptide), HSAN5, Beta-NGF
Ig Type	Rabbit IgG
克隆号	7R395
交叉反应	Human, Rat
验证活性	1. Western Blot -Positive WB detected in: U-87 whole cell lysate, Rat Brain whole cell lysate -All lanes: NGF antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 27 kDa -Observed band size: 39 kDa 2. IHC image of TMAH-00816 diluted at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
应用	ELISA, WB, IHC
推荐剂量	WB:1:500-1:5000; IHC:1:50-1:200.
抗体种类	Monoclonal
亚细胞定位	Secreted. Endosome lumen.
构建方式	Recombinant Antibody
纯化方式	Affinity-chromatography
性状	Liquid
缓冲液	Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景	Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (Probable). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone collapse. In contrast to mature NGF, the precursor form (proNGF) promotes neuronal apoptosis (in vitro). Inhibits metalloproteinase-dependent proteolysis of platelet glycoprotein VI. Binds lysophosphatidylinositol and lysophosphatidylserine between the two chains of the homodimer. The lipid-bound form promotes histamine relase from mast cells, contrary to the lipid-free form.