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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GLK Polyclonal Antibody 2

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货号 TMAB-06509

Anti-GLK Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 GLK。Anti-GLK Polyclonal Antibody 2 可用于 WB。

Anti-GLK Polyclonal Antibody 2

Anti-GLK Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-06509

Anti-GLK Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 GLK。Anti-GLK Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-GLK Polyclonal Antibody 2 is a Rabbit antibody targeting GLK. Anti-GLK Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Isoform 1 is expressed in pancreas. Isoform 2 and isoform 3 is expressed in liver.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Hexokinases phosphorylate glucose to produce glucose 6 phosphate, thus committing glucose to the glycolytic pathway. Alternative splicing of this gene results in three tissue specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose 6 phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non insulin dependent diabetes mellitus, also called maturity onset diabetes of the young, type 2; mutations have also been associated with persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
抗原信息
免疫原
KLH conjugated synthetic peptide: human GLK
抗原种属
Human
基因名称
GCK
基因ID
2645
蛋白名称
Hexokinase-4
Uniprot ID
P35557
功能
Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.
化学信息
分子量Theoretical: 51 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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