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Anti-NOX2 Antibody (5H588)

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货号 TMAB-09576

Anti-NOX2 Antibody (5H588) 是一种 Rabbit 抗体,靶向 NOX2。Anti-NOX2 Antibody (5H588) 可用于 WB。

Anti-NOX2 Antibody (5H588)

Anti-NOX2 Antibody (5H588)

一键复制产品信息
Rating icon 还可以
货号 TMAB-09576

Anti-NOX2 Antibody (5H588) 是一种 Rabbit 抗体,靶向 NOX2。Anti-NOX2 Antibody (5H588) 可用于 WB。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍


生物活性
产品描述
Anti-NOX2 Antibody (5H588) is a Rabbit antibody targeting NOX2. Anti-NOX2 Antibody (5H588) can be used in WB.
Ig Type
IgG
克隆号
5H588
反应种属
Human,Mouse,Rat
验证活性
25 μg total protein per lane of various lysates (see on figure) probed with NOX2 monoclonal antibody, unconjugated (TMAB-09576) at 1: 2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
应用WB
推荐剂量
WB: 1:1000-5000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Membrane.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景NOX2/gp91phox is a critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. It also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc. Defects in CYBB are a cause of X-linked chronic granulomatous disease (X-CGD). X-CGD is characterized by the failure of activated phagocytes to generate superoxide. Patients suffer from life-threatening bacterial/fungal infections.
抗原信息
免疫原
A synthesized peptide: human NOX2
抗原种属
Human
基因名称
CYBB
基因ID
蛋白名称
Cytochrome b-245 heavy chain
Uniprot ID
功能
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.
化学信息
分子量Theoretical: 65 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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