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Anti-NOX2 Antibody (5H588) 是一种 Rabbit 抗体,靶向 NOX2。Anti-NOX2 Antibody (5H588) 可用于 WB。
Anti-NOX2 Antibody (5H588) 是一种 Rabbit 抗体,靶向 NOX2。Anti-NOX2 Antibody (5H588) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 790 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
| 产品描述 | Anti-NOX2 Antibody (5H588) is a Rabbit antibody targeting NOX2. Anti-NOX2 Antibody (5H588) can be used in WB. |
| Ig Type | IgG |
| 克隆号 | 5H588 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WB |
| 推荐剂量 | WB: 1:1000-5000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | NOX2/gp91phox is a critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. It also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc. Defects in CYBB are a cause of X-linked chronic granulomatous disease (X-CGD). X-CGD is characterized by the failure of activated phagocytes to generate superoxide. Patients suffer from life-threatening bacterial/fungal infections. |
| 免疫原 | A synthesized peptide: human NOX2 |
| 抗原种属 | Human |
| 基因名称 | CYBB |
| 基因ID | |
| 蛋白名称 | Cytochrome b-245 heavy chain |
| Uniprot ID | |
| 功能 | Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc. |
| 分子量 | Theoretical: 65 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |