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Anti-Phospho-p73 (Tyr99) Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Phospho-p73 (Tyr99)。Anti-Phospho-p73 (Tyr99) Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。
Anti-Phospho-p73 (Tyr99) Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Phospho-p73 (Tyr99)。Anti-Phospho-p73 (Tyr99) Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-Phospho-p73 (Tyr99) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-p73 (Tyr99). Anti-Phospho-p73 (Tyr99) Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBIHC-PIHC-FrIF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. Cytoplasm. Note=Accumulates in the nucleus in response to DNA damage. |
| 组织特异性 | Expressed in striatal neurons of patients with Huntington disease (at protein level). Brain, kidney, placenta, colon, heart, liver, spleen, skeletal muscle, prostate, thymus and pancreas. Highly expressed in fetal tissue. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011]. |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human p73 around the phosphorylation site of Tyr99 |
| 抗原种属 | Human |
| 基因名称 | TP73 |
| 基因ID | |
| 蛋白名称 | Tumor protein p73 |
| Uniprot ID | |
| 功能 | Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. [COFACTOR] Binds 1 zinc ion per subunit |
| 分子量 | Theoretical: 70 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |