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Anti-SLAMF6 Antibody-PE (4Z355)
还可以产品编号 TMAY-02159P
Anti-SLAMF6 Antibody-PE (4Z355) 是一种 PE-conjugated Rabbit 抗体，靶向 SLAMF6。Anti-SLAMF6 Antibody-PE (4Z355) 可用于 FCM。
Anti-SLAMF6 Antibody-PE (4Z355)
Anti-SLAMF6 Antibody-PE (4Z355)
还可以产品编号 TMAY-02159P
Anti-SLAMF6 Antibody-PE (4Z355) 是一种 PE-conjugated Rabbit 抗体，靶向 SLAMF6。Anti-SLAMF6 Antibody-PE (4Z355) 可用于 FCM。
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| 产品描述 | Anti-SLAMF6 Antibody-PE (4Z355) is a PE-conjugated Rabbit antibody targeting SLAMF6. Anti-SLAMF6 Antibody-PE (4Z355) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 4Z355 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human SLAMF6(CD352) expression on human whole blood lymphocytes. Cells were stained with PE-conjugated anti-Human SLAMF6(CD352). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Ly108/SLAMF6 (rh Ly108/SLAMF6; TMPY-01914; Q96DU3-1; Met1-Met226) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 / Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6 / Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6 / Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6 / Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6 / Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/APC/FITC |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human Ly108/SLAMF6 Protein (TMPY-01914) |
| 抗原种属 | Human |
| 研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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