生物活性

产品描述	Siglec-10 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 Cells. The accession number is A0A2K5WBX8.
生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it.
研究背景	Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system.
种属	Cynomolgus
表达系统	HEK293 Cells
标签	C-His-Avi
蛋白编号	A0A2K5WBX8
蛋白构建	Thr17-Asn552
蛋白纯度	> 95% as determined by Bis-Tris PAGE
缓冲液	Supplied as 0.22 μm filtered solution in 25 mM MES, 150 mM NaCl, 0.5M Arginine (pH 5.0).
内毒素	< 1 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	61.71 kDa (Predicted); 72-82 kDa (Reducing condition, due to glycosylation)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

Siglec-10 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated

Siglec-10 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated

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