购物车
- 全部删除
您的购物车当前为空
Anti-IFNAR1 Antibody (4A488)
还可以产品编号 TMAY-03308
Anti-IFNAR1 Antibody (4A488) 是一种 Rabbit 抗体，靶向 IFNAR1。Anti-IFNAR1 Antibody (4A488) 可用于 ICC/IF。
Anti-IFNAR1 Antibody (4A488)
Anti-IFNAR1 Antibody (4A488)
还可以产品编号 TMAY-03308
Anti-IFNAR1 Antibody (4A488) 是一种 Rabbit 抗体，靶向 IFNAR1。Anti-IFNAR1 Antibody (4A488) 可用于 ICC/IF。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-IFNAR1 Antibody (4A488) is a Rabbit antibody targeting IFNAR1. Anti-IFNAR1 Antibody (4A488) can be used in ICC/IF. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 4A488 |
| 交叉反应 | Mouse |
| 验证活性 | Immunofluorescence staining of mouse IFNAR1 in mouse splenocytes. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with rabbit anti-mouse IFNAR1 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 594-conjugated Goat Anti-rabbit IgG secondary antibody (red) and counterstained with DAPI (blue). |
| 应用 | ICC/IF |
| 推荐剂量 | ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IFNAR1 (rM IFNAR1; TMPY-01489; NP_034638.2; Met1-Thr429). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor. Tyk2 slows down IFNAR1 degradation and that this is due, at least in part, to inhibition of IFNAR1 endocytosis. Mutant versions of IFNAR1, in which Tyr466 is changed to phenylalanine, can act in a dominant-negative manner to inhibit phosphorylation of STAT2. These observations are consistent with a model in which IFNAR1 mediates the interaction between JAK kinases and the STAT transcription factors. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse IFNAR1 Protein (TMPY-01489) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-IFNAR1 Antibody (4A488) | purchase Anti-IFNAR1 Antibody (4A488) | Anti-IFNAR1 Antibody (4A488) cost | order Anti-IFNAR1 Antibody (4A488)
嗨！有任何问题？点我咨询
评论内容