Anti-eIF3F Polyclonal Antibody is a Rabbit antibody targeting eIF3F. Anti-eIF3F Polyclonal Antibody can be used in WB.

IgG

Mouse (predicted:Human,Rat,Chicken,Dog,Cow,Horse)

WB: 1:500-2000

Polyclonal

KLH conjugated synthetic peptide: human eIF3F

Human

EIF3F

Eukaryotic translation initiation factor 3 subunit F

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.Deubiquitinates activated NOTCH1, promoting its nuclear import, thereby acting as a positive regulator of Notch signaling.