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Anti-BIRC5 Antibody (3G480)
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产品编号 TMAH-00115
别名 IAP4, EPR-1, BIRC5, baculoviral IAP repeat containing 5, API4
Anti-BIRC5 Antibody (3G480) 是一种抗体，靶向 BIRC5。Anti-BIRC5 Antibody (3G480) 可用于 ELISA, IHC。
Anti-BIRC5 Antibody (3G480)
Anti-BIRC5 Antibody (3G480)
还可以产品编号 TMAH-00115 别名 IAP4, EPR-1, BIRC5, baculoviral IAP repeat containing 5, API4
Anti-BIRC5 Antibody (3G480) 是一种抗体，靶向 BIRC5。Anti-BIRC5 Antibody (3G480) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,315 | 5日内发货 | |
| 100 μL | ¥ 2,185 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-BIRC5 Antibody (3G480) is an antibody targeting BIRC5. Anti-BIRC5 Antibody (3G480) can be used in ELISA, IHC. |
| 别名 | IAP4, EPR-1, BIRC5, baculoviral IAP repeat containing 5, API4 |
| Ig Type | Rabbit IgG |
| 克隆号 | 3G480 |
| 交叉反应 | Human |
| 验证活性 | IHC image of TMAH-00115 diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| 应用 | |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cytoplasm. Nucleus. Chromosome. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Midbody. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubules. Involved in the recruitment of CPC to centromeres during early mitosis via association with histone H3 phosphorylated at 'Thr-3' (H3pT3) during mitosis. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May counteract a default induction of apoptosis in G2/M phase. The acetylated form represses STAT3 transactivation of target gene promoters. May play a role in neoplasia. Inhibitor of CASP3 and CASP7. Essential for the maintenance of mitochondrial integrity and function. Isoform 2 and isoform 3 do not appear to play vital roles in mitosis. Isoform 3 shows a marked reduction in its anti-apoptotic effects when compared with the displayed wild-type isoform. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human Survivin |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Neuroscience, Cancer, Cell biology |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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