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别名 p35, NKSF1, NFSK, Interleukin-35, interleukin 12A, IL-35, IL-12A, CLMF
Anti-EBI3 Antibody (9P551) 是一种抗体,靶向 EBI3。Anti-EBI3 Antibody (9P551) 可用于 ELISA,WB。
Anti-EBI3 Antibody (9P551) 是一种抗体,靶向 EBI3。Anti-EBI3 Antibody (9P551) 可用于 ELISA,WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,310 | 5日内发货 | |
| 100 μL | ¥ 2,190 | 5日内发货 |
| 产品描述 | Anti-EBI3 Antibody (9P551) is an antibody targeting EBI3. Anti-EBI3 Antibody (9P551) can be used in ELISA,WB. |
| 别名 | p35, NKSF1, NFSK, Interleukin-35, interleukin 12A, IL-35, IL-12A, CLMF |
| Ig Type | Rabbit IgG |
| 克隆号 | 9P551 |
| 交叉反应 | Human |
| 验证活性 | Western Blot -Positive WB detected in: JK whole cell lysate -All lanes: EBI3 antibody at 1:500 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 25 kDa -Observed band size: 25 kDa |
| 应用 | ELISAWB |
| 推荐剂量 | WB:1:500-1:2000. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Secreted. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human EBI3 |
| 抗原种属 | Human |
| 基因名称 | EBI3 |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Cancer, Immunology |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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