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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Nogo R Polyclonal Antibody

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货号 TMAB-09557

Anti-Nogo R Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Nogo R。Anti-Nogo R Polyclonal Antibody 可用于 WB。

Anti-Nogo R Polyclonal Antibody

Anti-Nogo R Polyclonal Antibody

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货号 TMAB-09557

Anti-Nogo R Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Nogo R。Anti-Nogo R Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

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产品描述
Anti-Nogo R Polyclonal Antibody is a Rabbit antibody targeting Nogo R. Anti-Nogo R Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Lipid-anchor, GPI-anchor.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
浓度1mg/ml
研究背景Axons are essential for neuronal communication but they do not regenerate after injury to the adult mammalian brain or spinal cord. Failed regeneration is due in part to the production of a potent axonal growth inhibitor, Nogo, by myelinating cells. The finding of a high affinity axonal receptor for the extracellular domain of Nogo provides the first insight into the basis of Nogo action. Disrupting the interaction of Nogo with the Nogo-66 receptor may facilitate axonal regeneration in vivo. The protein is dubbed the Nogo receptor because it binds with several other proteins that block neural growth. It is found to be ubiquitous in the brain and spinal cord.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Nogo R
抗原种属
Human
基因名称
RTN4R
基因ID
65078
蛋白名称
Reticulon-4 receptor
Uniprot ID
Q9BZR6
功能
Receptor for RTN4, OMG and MAG. Mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Acts in conjunction with RTN4 and LIGO1 in regulating neuronal precursor cell motility during cortical development (By similarity).
化学信息
分子量Theoretical: 48 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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