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Cadherin 17/CDH17 Protein, Human, Recombinant (hFc)
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货号 TMPK-00948
别名 P130, MGC142024, MGC138218, LI-cadherin, HPT-1, FLJ26931, Cdh17, CDH16, Cadherin-17, cadherin-16, BILL-cadherin
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 111.73 kDa and the accession number is Q12864.
其他形式的 “Cadherin 17/CDH17 Protein, Human, Recombinant (hFc)”:
Cadherin 17/CDH17 Protein, Human, Recombinant (hFc)
一键复制产品信息 还可以SPR兼容缓冲液
货号 TMPK-00948 别名 P130, MGC142024, MGC138218, LI-cadherin, HPT-1, FLJ26931, Cdh17, CDH16, Cadherin-17, cadherin-16, BILL-cadherin
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 111.73 kDa and the accession number is Q12864.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 343 | 6-8日内发货 | |
| 10 μg | ¥ 549 | 6-8日内发货 | |
| 20 μg | ¥ 898 | 5日内发货 | |
| 50 μg | ¥ 1,760 | 5日内发货 | |
| 100 μg | ¥ 2,960 | 5日内发货 | |
| 200 μg | ¥ 5,350 | 5日内发货 | |
| 500 μg | ¥ 11,800 | 5日内发货 |
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| 产品描述 | Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 111.73 kDa and the accession number is Q12864. |
| 生物活性 | Immobilized Human CDH17, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-CDH17 Antibody, hFc Tag with the EC50 of 14.8ng/ml determined by ELISA. |
| 研究背景 | Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-hFc |
| 蛋白编号 | Q12864 |
| 蛋白构建 | Gln23-Met787 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | P130, MGC142024, MGC138218, LI-cadherin, HPT-1, FLJ26931, Cdh17, CDH16, Cadherin-17, cadherin-16, BILL-cadherin |
| 内毒素 | < 1 EU/μg by the LAL method. |
| 分子量 | 111.73 kDa (predicted). Due to glycosylation, the protein migrates to 113-135 kDa based on Tris-Bis PAGE result. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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