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顶部生物活性储存和溶解信息计算器

Anti-TRXR1/TXNRD1 Antibody (5M66)

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Anti-TRXR1/TXNRD1 Antibody (5M66)
产品编号 TMAY-02474
别名 TXNR, TRXR1, TR1, TR, thioredoxin reductase 1, GRIM-12

Anti-TRXR1/TXNRD1 Antibody (5M66) 是一种 Mouse 抗体，靶向 TRXR1/TXNRD1。Anti-TRXR1/TXNRD1 Antibody (5M66) 可用于 FCM,ICC/IF。

Anti-TRXR1/TXNRD1 Antibody (5M66)
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Anti-TRXR1/TXNRD1 Antibody (5M66)

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Anti-TRXR1/TXNRD1 Antibody (5M66)
产品编号 TMAY-02474 别名 TXNR, TRXR1, TR1, TR, thioredoxin reductase 1, GRIM-12

Anti-TRXR1/TXNRD1 Antibody (5M66) 是一种 Mouse 抗体，靶向 TRXR1/TXNRD1。Anti-TRXR1/TXNRD1 Antibody (5M66) 可用于 FCM,ICC/IF。

规格价格库存数量
100 μL
¥ 1,689
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产品介绍

生物活性
产品描述
Anti-TRXR1/TXNRD1 Antibody (5M66) is a Mouse antibody targeting TRXR1/TXNRD1. Anti-TRXR1/TXNRD1 Antibody (5M66) can be used in FCM,ICC/IF.
别名TXNR, TRXR1, TR1, TR, thioredoxin reductase 1, GRIM-12
Ig Type
Mouse IgG1
克隆号
5M66
交叉反应
Human
验证活性
1. Immunofluorescence staining of Human TXNRD1 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with mouse anti-Human TXNRD1 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-mouse IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm and nucleus.
2. Flow cytometric analysis of Human TXNRD1 expression on HeLa cells.  The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human C1QBP, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用
FCM,ICC/IF
推荐剂量
ICC-IF: 1:20-1:100; FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Mouse
构建方式This product is a recombinant monoclonal antibody expressed from HEK293 cells.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor the development of Drug-induced liver injury (DILI), which is the most common adverse drug reaction.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human TXNRD1 protein (TMPY-02271)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

TRXR-1TRXR 1TR-1TR 1GRIM12GRIM 12

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