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Anti-HEXB chain B Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HEXB chain B。Anti-HEXB chain B Polyclonal Antibody 可用于 WB。
Anti-HEXB chain B Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HEXB chain B。Anti-HEXB chain B Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-HEXB chain B Polyclonal Antibody is a Rabbit antibody targeting HEXB chain B. Anti-HEXB chain B Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse (predicted:Rat,Dog,Cow,Sheep) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Lysosome. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Hexosaminidase B is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). [provided by RefSeq, Jul 2008]. |
| 免疫原 | KLH conjugated synthetic peptide: human HEXB |
| 抗原种属 | Human |
| 基因名称 | HEXB |
| 基因ID | |
| 蛋白名称 | beta-hexosaminidase subunit beta |
| Uniprot ID | |
| 功能 | Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. |
| 分子量 | Theoretical: 22/50 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |