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Anti-CD4 Antibody (6H844)

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货号 TMAB-03982

Anti-CD4 Antibody (6H844) 是一种 Rabbit 抗体，靶向 CD4。Anti-CD4 Antibody (6H844) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-CD4 Antibody (6H844)

Anti-CD4 Antibody (6H844)

一键复制产品信息
Rating icon 还可以
货号 TMAB-03982

Anti-CD4 Antibody (6H844) 是一种 Rabbit 抗体，靶向 CD4。Anti-CD4 Antibody (6H844) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD4 Antibody (6H844) is a Rabbit antibody targeting CD4. Anti-CD4 Antibody (6H844) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
6H844
反应种属
Mouse
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-5000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type I membrane protein. Note=Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum.
构建方式Recombinant Antibody
纯化方式Protein A purified
缓冲液PBS with 0.02% Proclin300,100 μg/ml BSA and 50% glycerol.
浓度1mg/ml
研究背景This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010].
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse CD4
抗原种属
Mouse
基因名称
CD4
基因ID
12504
蛋白名称
T-cell surface glycoprotein CD4
Uniprot ID
P06332
功能
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
化学信息
分子量Theoretical: 51 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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