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Anti-EGFR Antibody (1W39) 是一种 Rabbit 抗体,靶向 EGFR。Anti-EGFR Antibody (1W39) 可用于 ELISA,FCM。
Anti-EGFR Antibody (1W39) 是一种 Rabbit 抗体,靶向 EGFR。Anti-EGFR Antibody (1W39) 可用于 ELISA,FCM。
产品描述 | Anti-EGFR Antibody (1W39) is a Rabbit antibody targeting EGFR. Anti-EGFR Antibody (1W39) can be used in ELISA,FCM. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 1W39 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of Human EGFR expression on A431 cells. Cells were stained with purified anti-Human EGFR, then a FITC-conjugated second step antibody. The histogram were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
应用 | ELISA,FCM |
推荐剂量 | ELISA: 1:5000-1:10000; FCM: 1:25-1:100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human EGFR / HER1 / ErbB1 (rh EGFR / HER1 / ErbB1; TMPY-00742; NP_005219; Met1-Ser645). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
偶联 | Unconjugated |
其他可选修饰符 | APC/FITC/PE |
可提供抗体种类 | 4 |
免疫原 | Recombinant Human EGFR / HER1 / ErbB1 Protein (TMPY-00742) |
抗原种属 | Human |
研究领域 | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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