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Anti-NAV1.7 Polyclonal Antibody

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货号 TMAB-01203

别名 Voltage gated sodium channel subunit alpha Nav1, Voltage gated sodium channel alpha subunit Nav1.7, Sodium channel voltage gated type IX alpha subunit, Sodium channel voltage gated type IX alpha polypeptide, Sodium channel voltage gated type IX alpha, Sodium channel protein type IX subunit alpha, Sodium channel protein type 9 subunit alpha, SCN9A, PN1, Peripheral sodium channel 1, Neuroendocrine sodium channel, NENA, NE NA, hNENa, hNE Na, FEB3B, ETHA

Anti-NAV1.7 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 NAV1.7。Anti-NAV1.7 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

Anti-NAV1.7 Polyclonal Antibody

Anti-NAV1.7 Polyclonal Antibody

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货号 TMAB-01203 别名 Voltage gated sodium channel subunit alpha Nav1, Voltage gated sodium channel alpha subunit Nav1.7, Sodium channel voltage gated type IX alpha subunit, Sodium channel voltage gated type IX alpha polypeptide, Sodium channel voltage gated type IX alpha, Sodium channel protein type IX subunit alpha, Sodium channel protein type 9 subunit alpha, SCN9A, PN1, Peripheral sodium channel 1, Neuroendocrine sodium channel, NENA, NE NA, hNENa, hNE Na, FEB3B, ETHA

Anti-NAV1.7 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 NAV1.7。Anti-NAV1.7 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-NAV1.7 Polyclonal Antibody is a Rabbit antibody targeting NAV1.7. Anti-NAV1.7 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
别名Voltage gated sodium channel subunit alpha Nav1, Voltage gated sodium channel alpha subunit Nav1.7, Sodium channel voltage gated type IX alpha subunit, Sodium channel voltage gated type IX alpha polypeptide, Sodium channel voltage gated type IX alpha, Sodium channel protein type IX subunit alpha, Sodium channel protein type 9 subunit alpha, SCN9A, PN1, Peripheral sodium channel 1, Neuroendocrine sodium channel, NENA, NE NA, hNENa, hNE Na, FEB3B, ETHA
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Pig,Cow,Rabbit,Sheep)
验证活性
Paraformaldehyde-fixed, paraffin embedded (rat brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (NAV1.7) Polyclonal Antibody, Unconjugated (TMAB-01203) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
verifiedActivity
应用IFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein. Note=In neurite terminals.
组织特异性Expressed strongly in dorsal root ganglion, with only minor levels elsewhere in the body, smooth muscle cells, MTC cell line and C-cell carcinoma. Isoform 1 is expressed preferentially in the central and peripheral nervous system. Isoform 2 is expressed p
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. [provided by RefSeq, Aug 2009]
抗原信息
免疫原
KLH conjugated synthetic peptide: human NAV1.7
抗原种属
Human
基因名称
SCN9A
基因ID
蛋白名称
Sodium channel protein type 9 subunit alpha
Uniprot ID
研究领域
Channels,Sodium Channels,Cancer
功能
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na(+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain.
化学信息
分子量Theoretical: 219 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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