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别名 Voltage gated sodium channel subunit alpha Nav1, Voltage gated sodium channel alpha subunit Nav1.7, Sodium channel voltage gated type IX alpha subunit, Sodium channel voltage gated type IX alpha polypeptide, Sodium channel voltage gated type IX alpha, Sodium channel protein type IX subunit alpha, Sodium channel protein type 9 subunit alpha, SCN9A, PN1, Peripheral sodium channel 1, Neuroendocrine sodium channel, NENA, NE NA, hNENa, hNE Na, FEB3B, ETHA
Anti-NAV1.7 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 NAV1.7。Anti-NAV1.7 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。
Anti-NAV1.7 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 NAV1.7。Anti-NAV1.7 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-NAV1.7 Polyclonal Antibody is a Rabbit antibody targeting NAV1.7. Anti-NAV1.7 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
| 别名 | Voltage gated sodium channel subunit alpha Nav1, Voltage gated sodium channel alpha subunit Nav1.7, Sodium channel voltage gated type IX alpha subunit, Sodium channel voltage gated type IX alpha polypeptide, Sodium channel voltage gated type IX alpha, Sodium channel protein type IX subunit alpha, Sodium channel protein type 9 subunit alpha, SCN9A, PN1, Peripheral sodium channel 1, Neuroendocrine sodium channel, NENA, NE NA, hNENa, hNE Na, FEB3B, ETHA |
| Ig Type | IgG |
| 反应种属 | Rat (predicted:Human,Mouse,Pig,Cow,Rabbit,Sheep) |
| 验证活性 | Paraformaldehyde-fixed, paraffin embedded (rat brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (NAV1.7) Polyclonal Antibody, Unconjugated (TMAB-01203) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining. ![]() |
| 应用 | IFIHC-FrIHC-P |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. Note=In neurite terminals. |
| 组织特异性 | Expressed strongly in dorsal root ganglion, with only minor levels elsewhere in the body, smooth muscle cells, MTC cell line and C-cell carcinoma. Isoform 1 is expressed preferentially in the central and peripheral nervous system. Isoform 2 is expressed p |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. [provided by RefSeq, Aug 2009] |
| 免疫原 | KLH conjugated synthetic peptide: human NAV1.7 |
| 抗原种属 | Human |
| 基因名称 | SCN9A |
| 基因ID | |
| 蛋白名称 | Sodium channel protein type 9 subunit alpha |
| Uniprot ID | |
| 研究领域 | Channels,Sodium Channels,Cancer |
| 功能 | Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na(+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain. |
| 分子量 | Theoretical: 219 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | store at -20°C |