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Anti-CHX10 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CHX10。Anti-CHX10 Polyclonal Antibody 可用于 WB,ELISA。
Anti-CHX10 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CHX10。Anti-CHX10 Polyclonal Antibody 可用于 WB,ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 |
| 产品描述 | Anti-CHX10 Polyclonal Antibody is a Rabbit antibody targeting CHX10. Anti-CHX10 Polyclonal Antibody can be used in WB,ELISA. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse |
| 应用 | WBELISA |
| 推荐剂量 | WB: 1:500-2000; ELISA: 1:5000-10000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Abundantly expressed in retinal neuroblasts during eye development and in the inner nuclear layer of the adult retina. Within this layer, expression is stronger in the outer margin where bipolar cells predominate. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | CHX10 is a 40kDa homeodomain protein of the paired-like class that is essential for development of the mammalian eye. Mutations in CHX10 cause microphthalmia, a cause of congenital blindness in humans, and the ocular retardation (or) phenotype in mice. In the developing mouse retina CHX10 is expressed in retinal progenitors, while in the mature retina, CHX10 expression becomes restricted to bipolar neurons. Concurrent with these expression patterns, the CHX10-/- (or) retina is thin due to a defect in proliferation of retinal progenitors, and lacks bipolar neurons. CHX10 is also expressed in the developing brainstem, thalamus, and spinal cord. |
| 免疫原 | KLH conjugated synthetic peptide: human CHX10 |
| 抗原种属 | Human |
| 基因名称 | VSX2 |
| 基因ID | |
| 蛋白名称 | Visual system homeobox 2 |
| Uniprot ID | |
| 功能 | Plays a significant role in the specification and morphogenesis of the sensory retina. May also participate in the development of the cells of the inner nuclear layer, particularly bipolar cells (By similarity). |
| 分子量 | Theoretical: 40 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |