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Anti-HIP1 Antibody (5F230) 是一种 Rabbit 抗体,靶向 HIP1。Anti-HIP1 Antibody (5F230) 可用于 WB,ICC/IF,IP。
Anti-HIP1 Antibody (5F230) 是一种 Rabbit 抗体,靶向 HIP1。Anti-HIP1 Antibody (5F230) 可用于 WB,ICC/IF,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 795 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-HIP1 Antibody (5F230) is a Rabbit antibody targeting HIP1. Anti-HIP1 Antibody (5F230) can be used in WB,ICC/IF,IP. |
| Ig Type | IgG |
| 克隆号 | 5F230 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBICC/IFIP |
| 推荐剂量 | WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Nucleus. Endomembrane system. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Shuttles between cytoplasm and nucleus. Nuclear translocation can be induced by AR. |
| 组织特异性 | Ubiquitously expressed with the highest level in brain. Expression is up-regulated in prostate and colon cancer. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Plays a role in clathrin-mediated endocytosis and trafficking .Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner.Regulates presynaptic nerve terminal activity. |
| 免疫原 | A synthesized peptide: human HIP 1 |
| 抗原种属 | Human |
| 基因名称 | HIP1 |
| 基因ID | |
| 蛋白名称 | Huntingtin-interacting protein 1 |
| Uniprot ID | |
| 功能 | Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Enhances androgen receptor (AR)-mediated transcription. May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. May play a functional role in the cell filament networks. May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors. |
| 分子量 | Theoretical: 116 kDa. Actual: 116 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |