Anti-FTO Antibody (6A98)

Name: Anti-FTO Antibody (6A98)
Brand: TargetMol
SKU: TMAC-01569
Rating: 4.5 (1 reviews)

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产品编号 TMAC-01569

Anti-FTO Antibody (6A98) 是一种 Rabbit 抗体，靶向 FTO。Anti-FTO Antibody (6A98) 可用于 WB,ICC/IF,IHC。

Anti-FTO Antibody (6A98)

还可以

产品编号 TMAC-01569

Anti-FTO Antibody (6A98) 是一种 Rabbit 抗体，靶向 FTO。Anti-FTO Antibody (6A98) 可用于 WB,ICC/IF,IHC。

规格	价格	库存	数量
50 μL	¥ 1,490	5日内发货
100 μL	¥ 2,490	5日内发货

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产品描述	Anti-FTO Antibody (6A98) is a Rabbit antibody targeting FTO. Anti-FTO Antibody (6A98) can be used in WB,ICC/IF,IHC.
Ig Type	IgG
克隆号	6A98
交叉反应	Human
验证活性	1. Western blot analysis of FTO on different lysates using anti-FTO antibody at 1/1,000 dilution. Positive control: Lane 1: Human fetal brain tissue, Lane 2: HepG2, Lane 3: 293. 2. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-FTO antibody. Counter stained with hematoxylin.
应用	WB ICC/IF IHC
推荐剂量	WB: 1:500-2000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类	Monoclonal
宿主来源	Rabbit
构建方式	Recombinant Antibody
纯化方式	ProA affinity purified
性状	Liquid
缓冲液	1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景	FTO, also known as Fatso or KIAA1752, is a 505 amino acid protein that has an N-terminal nuclear localization signal. Expressed in a variety of tissues, with highest levels present in brain and pancreatic tissue, Fatso exists as four alternatively spliced isoforms, one of which is associated with a predisposition to childhood and adult obesity. Due to its involvement in the development of obesity, Fatso is associated with an increased BMI and may be involved in the pathogenesis of type 2 diabetes. The gene encoding Fatso maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.