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Anti-Vitamin D Receptor/VDR Antibody (5I578)
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产品编号 TMAH-01244
别名 vitamin D (1,25- dihydroxyvitamin D3) receptor, PPP1R163, NR1I1
Anti-Vitamin D Receptor/VDR Antibody (5I578) 是一种抗体，靶向 Vitamin D Receptor/VDR。Anti-Vitamin D Receptor/VDR Antibody (5I578) 可用于 ELISA, WB, IHC。
Anti-Vitamin D Receptor/VDR Antibody (5I578)
Anti-Vitamin D Receptor/VDR Antibody (5I578)
还可以产品编号 TMAH-01244 别名 vitamin D (1,25- dihydroxyvitamin D3) receptor, PPP1R163, NR1I1
Anti-Vitamin D Receptor/VDR Antibody (5I578) 是一种抗体，靶向 Vitamin D Receptor/VDR。Anti-Vitamin D Receptor/VDR Antibody (5I578) 可用于 ELISA, WB, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,315 | 5日内发货 | |
| 100 μL | ¥ 2,195 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Vitamin D Receptor/VDR Antibody (5I578) is an antibody targeting Vitamin D Receptor/VDR. Anti-Vitamin D Receptor/VDR Antibody (5I578) can be used in ELISA, WB, IHC. |
| 别名 | vitamin D (1,25- dihydroxyvitamin D3) receptor, PPP1R163, NR1I1 |
| Ig Type | Rabbit IgG |
| 克隆号 | 5I578 |
| 交叉反应 | Human |
| 验证活性 | 1. Western Blot -Positive WB detected in: MCF-7 whole cell lysate, THP-1 whole cell lysate, HL-60 whole cell lysate -All lanes: Vitamin D antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 49, 54 kDa -Observed band size: 49 kDa 2. IHC image of TMAH-01244 diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| 应用 | |
| 推荐剂量 | WB:1:500-1:5000; IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Nucleus. Cytoplasm. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR. The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes. Plays a central role in calcium homeostasis. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human Vitamin D Receptor |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Epigenetics and Nuclear Signaling, Cancer, Signal transduction |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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