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Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody 2

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Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody 2
产品编号 TMAC-00538
别名 p-CAMKII alpha/beta/gamma (Thr305), p-CAMKII alpha/beta/gamma (T305), CAMKII alpha/beta/gamma (p-Thr305), CAMKII alpha/beta/gamma (p-T305)

Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-CAMKII alpha/beta/gamma (Thr305)。Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody 可用于 WB,IHC,IF。

Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody 2

Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody 2

Rating icon 还可以
Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody 2
产品编号 TMAC-00538 别名 p-CAMKII alpha/beta/gamma (Thr305), p-CAMKII alpha/beta/gamma (T305), CAMKII alpha/beta/gamma (p-Thr305), CAMKII alpha/beta/gamma (p-T305)

Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-CAMKII alpha/beta/gamma (Thr305)。Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody 可用于 WB,IHC,IF。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,240
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CAMKII alpha/beta/gamma (Thr305). Anti-Phospho-CAMKII alpha/beta/gamma (Thr305) Polyclonal Antibody can be used in WB,IHC,IF.
别名p-CAMKII alpha/beta/gamma (Thr305), p-CAMKII alpha/beta/gamma (T305), CAMKII alpha/beta/gamma (p-Thr305), CAMKII alpha/beta/gamma (p-T305)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Immunohistochemical analysis of paraffin-embedded human brain tissue using CaMKII (Phospho-Thr305) antibody TMAC-00538 (left) or the same antibody preincubated with blocking peptide (right).
2. Western Blot analysis of 453 cells using Phospho-CaMKIIα/β/δ (T305) Polyclonal Antibody diluted at 1:1000.
应用
WB
IHC
IF
推荐剂量
WB: 1:500-2000; IHC: 1:100-300; IF: 1:50-200
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
性状Liquid
缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
研究背景Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling. Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human CaMK2 alpha/beta/delta around the phosphorylation site of Thr305
抗原种属
human
Uniprot ID
Q9UQM7 & Q13554 & Q13555
化学信息
分子量Actual: 54 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pCAMKII alpha/beta/gamma (Thr305)pCAMKII alpha/beta/gamma (T305)CAMKII alpha/beta/gamma (pThr305)CAMKII alpha/beta/gamma (pT305)CAMKII alpha/beta/gamma (phospho-Thr305)CAMKII alpha/beta/gamma (phospho-T305)

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