购物车
  • 全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部生物活性储存和溶解信息计算器

Anti-Phospho-FOXO1/3/4 (Thr24/32) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-FOXO1/3/4 (Thr24/32) Polyclonal Antibody
产品编号 TMAC-01541
别名 p-FOXO1/3/4 (Thr24/32), p-FOXO1/3/4 (T24/32), FOXO1/3/4 (p-Thr24/32), FOXO1/3/4 (p-T24/32)

Anti-Phospho-FOXO1/3/4 (Thr24/32) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-FOXO1/3/4 (Thr24/32)。Anti-Phospho-FOXO1/3/4 (Thr24/32) Polyclonal Antibody 可用于 WB。

Anti-Phospho-FOXO1/3/4 (Thr24/32) Polyclonal Antibody

Anti-Phospho-FOXO1/3/4 (Thr24/32) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-FOXO1/3/4 (Thr24/32) Polyclonal Antibody
产品编号 TMAC-01541 别名 p-FOXO1/3/4 (Thr24/32), p-FOXO1/3/4 (T24/32), FOXO1/3/4 (p-Thr24/32), FOXO1/3/4 (p-T24/32)

Anti-Phospho-FOXO1/3/4 (Thr24/32) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-FOXO1/3/4 (Thr24/32)。Anti-Phospho-FOXO1/3/4 (Thr24/32) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,245
5日内发货
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
联系我们获取更多批次信息
资源下载
产品操作手册

产品介绍

生物活性
产品描述
Anti-Phospho-FOXO1/3/4 (Thr24/32) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FOXO1/3/4 (Thr24/32). Anti-Phospho-FOXO1/3/4 (Thr24/32) Polyclonal Antibody can be used in WB.
别名p-FOXO1/3/4 (Thr24/32), p-FOXO1/3/4 (T24/32), FOXO1/3/4 (p-Thr24/32), FOXO1/3/4 (p-T24/32)
Ig Type
IgG
交叉反应
Human,Mouse
验证活性
1. Western blot analysis of extracts from 293 cells treated with Serum using FOXO1/3/4-pan (Phospho-Thr24/32) Antibody TMAC-01541. The lane on the right is treated with the antigen-specific peptide.
应用
WB
推荐剂量
WB: 1:500-1000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts syngernistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A to activate the expression of genes such as IGFBP1, G6PC and PPCK1. Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1. Promotes neural cell death. Mediates insulin action on adipose. Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake. Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of threonine 24/32(S-C-T(p)-W-P) derived from Human FOXO1/3/4-pan
抗原种属
human
Uniprot ID
Q12778 & O43524 & P98177
化学信息
分子量Actual: 78 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器

关键词

pFOXO1/3/4 (Thr24/32)pFOXO1/3/4 (T24/32)FOXO1/3/4 (pThr24/32)FOXO1/3/4 (pT24/32)FOXO1/3/4 (phospho-Thr24/32)FOXO1/3/4 (phospho-T24/32)

评论列表

4个月前
5.0
Rating icon 很棒

评论内容

233
Related Tags: buy Anti-Phospho-FOXO1/3/4 (Thr24/32) Polyclonal Antibody | purchase Anti-Phospho-FOXO1/3/4 (Thr24/32) Polyclonal Antibody | Anti-Phospho-FOXO1/3/4 (Thr24/32) Polyclonal Antibody cost | order Anti-Phospho-FOXO1/3/4 (Thr24/32) Polyclonal Antibody | Anti-Phospho-FOXO1/3/4 (Thr24/32) Polyclonal Antibody molecular weight