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Anti-DOCK9 Polyclonal Antibody

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货号 TMAB-05274

Anti-DOCK9 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 DOCK9。Anti-DOCK9 Polyclonal Antibody 可用于 WB。

Anti-DOCK9 Polyclonal Antibody

Anti-DOCK9 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05274

Anti-DOCK9 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 DOCK9。Anti-DOCK9 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-DOCK9 Polyclonal Antibody is a Rabbit antibody targeting DOCK9. Anti-DOCK9 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Intracytoplasmic membrane
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景DOCK9 is a 2,069 amino acid protein that localizes to the intracytoplasmic membrane and contains one PH domain, one DHR-1 domain and one DHR-2 domain. Expressed in a variety of tissues with highest expression in placenta and heart and lower expression in lung, kidney, brain and skeletal muscle, Zizimin-1 functions as a guanine nucleotide-exchange factor (GEF) that specifically activates Cdc42 by exchanging bound GDP for free GTP. Four isoforms of Zizimin-1 exist due to alternative splicing events. The gene encoding Zizimin-1 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DOCK9
抗原种属
Human
基因名称
DOCK9
基因ID
蛋白名称
Dedicator of cytokinesis protein 9
Uniprot ID
功能
DOCK9 is a guanine nucleotide exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Its overexpression induces filopodia formation.
化学信息
分子量Theoretical: 236 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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