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顶部生物活性储存和溶解信息计算器

Anti-AP2 beta Antibody (6Y40)

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Anti-AP2 beta Antibody (6Y40)
产品编号 TMAC-00231
别名 Transcription factor AP-2-beta, Transcription factor AP2 beta, Transcription factor AP 2 beta, Tfap2b, TFAP 2B, PDA2, OTTHUMP00000039925, MGC21381, AP2β, AP2-beta, AP2beta, AP2B_HUMAN, AP2B, AP2 β, AP2 B, AP 2B, Activating enhancer-binding protein 2-beta, Activating enhancer binding protein 2 beta

Anti-AP2 beta Antibody (6Y40) 是一种 Mouse 抗体，靶向 AP2 beta。Anti-AP2 beta Antibody (6Y40) 可用于 WB,FCM。

Anti-AP2 beta Antibody (6Y40)

Anti-AP2 beta Antibody (6Y40)

Rating icon 还可以
Anti-AP2 beta Antibody (6Y40)
产品编号 TMAC-00231 别名 Transcription factor AP-2-beta, Transcription factor AP2 beta, Transcription factor AP 2 beta, Tfap2b, TFAP 2B, PDA2, OTTHUMP00000039925, MGC21381, AP2β, AP2-beta, AP2beta, AP2B_HUMAN, AP2B, AP2 β, AP2 B, AP 2B, Activating enhancer-binding protein 2-beta, Activating enhancer binding protein 2 beta

Anti-AP2 beta Antibody (6Y40) 是一种 Mouse 抗体，靶向 AP2 beta。Anti-AP2 beta Antibody (6Y40) 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,995
5日内发货
100 μL
¥ 2,980
5日内发货
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产品介绍

生物活性
产品描述
Anti-AP2 beta Antibody (6Y40) is a Mouse antibody targeting AP2 beta. Anti-AP2 beta Antibody (6Y40) can be used in WB,FCM.
别名Transcription factor AP-2-beta, Transcription factor AP2 beta, Transcription factor AP 2 beta, Tfap2b, TFAP 2B, PDA2, OTTHUMP00000039925, MGC21381, AP2β, AP2-beta, AP2beta, AP2B_HUMAN, AP2B, AP2 β, AP2 B, AP 2B, Activating enhancer-binding protein 2-beta, Activating enhancer binding protein 2 beta
克隆号
6Y40
交叉反应
Human
验证活性
1. Western blot analysis of AP2 beta on human AP2 beta recombinant protein using anti- AP2 beta antibody at 1/1,000 dilution.
2. Western blot analysis of AP2 beta on HEK293 (1) and AP2 beta -hIgGFc transfected HEK293 (2) cell lysate using anti- AP2 beta antibody at 1/1,000 dilution.
3. Western blot analysis of AP2 beta on SK-N-SH cell lysate using anti- AP2 beta antibody at 1/1,000 dilution.
4. Flow cytometric analysis of SK-N-SH cells with AP2 beta antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
应用
WB
FCM
推荐剂量
WB: 1:500-2000; FCM: 1:100-200
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景AP-2 transcription factor family members include AP-2α, AP-2β and AP-2γ, which specifically bind to the DNA consensus sequence CCCCAGGC and initiate transcription of selected genes. AP-2, also known as ERF-1, plays a role in regulating estrogen receptor expression. AP-2β, a splice variant of AP-2α, inhibits AP-2 activity. Besides subscribing to the AP-2 complex, AP-2α, AP-2β and AP-2γ proteins compose the OB2-1 transcription factor complex. OB2-1 specifically upregulates expression of the proto-oncogene c-ErbB-2, which is overexpressed in 25-30% of breast cancers. AP-2α may play an important role in the development of ectodermal-derived tissues. Deleterious mutations involving the AP-2α gene are linked to microphthalmia, corneal clouding and other anterior eye chamber defects. The ubiquitously expressed AP-4 transcription factor specifically binds to the DNA consensus sequence 5'-CAGCTG-3'. AP-4 interacts with promoters for immunoglobulin-κ gene families and simian virus 40. AP-4 may enhance the transcription of the human Huntington's disease gene. AP-4 is a helix-loop-helix protein that contains two distinctive leucine repeat elements.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q92481
化学信息
分子量Theoretical: 50 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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