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Anti-CD64 Antibody-FITC (1I453)

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产品编号 TMAY-00524F

Anti-CD64 Antibody-FITC (1I453) 是一种 FITC-conjugated Rabbit 抗体,靶向 CD64。Anti-CD64 Antibody-FITC (1I453) 可用于 FCM。

Anti-CD64 Antibody-FITC (1I453)

Anti-CD64 Antibody-FITC (1I453)

Rating icon 还可以
产品编号 TMAY-00524F

Anti-CD64 Antibody-FITC (1I453) 是一种 FITC-conjugated Rabbit 抗体,靶向 CD64。Anti-CD64 Antibody-FITC (1I453) 可用于 FCM。

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产品介绍

生物活性
产品描述
Anti-CD64 Antibody-FITC (1I453) is a FITC-conjugated Rabbit antibody targeting CD64. Anti-CD64 Antibody-FITC (1I453) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
克隆号
1I453
交叉反应
Human
验证活性
Flow cytometric analysis of Human CD64 expression on human whole blood monocytes. Cells were stained with FITC-conjugated anti-Human CD64. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
应用
FCM
推荐剂量
5 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human CD64/Fc gamma RI (rh CD64/Fc gamma RI; TMPY-04261; NP_000557.1; Met1-Pro288) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.09% sodium azide
研究背景High affinity immunoglobulin gamma Fc receptor I, also known as FCGR1 and CD64, is an integral membraneglycoprotein and a member of the immunoglobulin superfamily. CD64 is a high affinity receptor for the Fc region of IgG gamma and functions in both innate and adaptive immune responses. Receptors that recognize the Fc portion of IgG function in the regulation of immune response and are divided into three classes designated CD64, CD32, and CD16. CD64 is structurally composed of asignal peptidethat allows its transport to the surface of a cell, threeextracellularimmunoglobulin domainsof the C2-type that it uses to bind antibody, a hydrophobictransmembrane domain, and a short cytoplasmic tail. CD64 isconstitutivelyfound on only macrophages and monocytes, but treatment of polymorphonuclear leukocyteswith cytokines likeIFNγandG-CSFcan induce CD64 expression on these cells. The inactivation of the mouse CD64 resulted in a wide range of defects in antibody Fc-dependent functions. Mouse CD64 is an early participant in Fc-dependent cell activation and in the development of immune responses.
偶联与修饰
偶联
FITC
其他可选修饰符
Unconjugated/APC/PerCP/PE
可提供抗体种类
5
抗原信息
免疫原
Recombinant Human CD64/Fc gamma RI Protein (TMPY-04261)
抗原种属
Human
研究领域
Fc Receptors
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
运输方式Shipping with blue ice.

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4个月前
5.0
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