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Anti-HER2/ERBB2 Antibody (2P27) 是一种 Mouse 抗体,靶向 HER2/ERBB2。Anti-HER2/ERBB2 Antibody (2P27) 可用于 ELISA,WB,IHC。
Anti-HER2/ERBB2 Antibody (2P27) 是一种 Mouse 抗体,靶向 HER2/ERBB2。Anti-HER2/ERBB2 Antibody (2P27) 可用于 ELISA,WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,345 | 5日内发货 | |
100 μL | ¥ 2,185 | 5日内发货 |
产品描述 | Anti-HER2/ERBB2 Antibody (2P27) is a Mouse antibody targeting HER2/ERBB2. Anti-HER2/ERBB2 Antibody (2P27) can be used in ELISA,WB,IHC. |
别名 | TKR1, NGL, NEU, MLN19, MLN 19, HERVW, HERV7Q, herstatin, HER-2, HER2, ERVWE1, ERBB2, ENVW, ENV, EGFR2, CD340 |
克隆号 | 2P27 |
交叉反应 | Human |
验证活性 | 1. Western blot analysis using Her2 mouse mAb against SKBR3 (1) and MCF-7 (2) cell lysate. |
应用 | |
推荐剂量 | ELISA: 1:10000; WB: 1:500-2000; IHC: 1:200-1000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | Affinity-chromatography |
性状 | Liquid |
缓冲液 | Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein: human Her2 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 180 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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