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Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-CDK1 (Thr14)。Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody 可用于 WB。
Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-CDK1 (Thr14)。Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,245 | 5日内发货 |
产品描述 | Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDK1 (Thr14). Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody can be used in WB. |
别名 | p-CDK1 (Thr14), p-CDK1 (T14), CDK1 (p-Thr14), CDK1 (p-T14) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of extracts from HepG2 cells treated with Forskolin using Phospho-CDK1/CDC2 (Thr14) antibody TMAC-00786. The lane on the right is treated with the antigen-specific peptide. |
应用 | |
推荐剂量 | WB: 1:500-1000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Interacts with cyclins A, B1, B3, D, or E. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phospho rylation site of threonine14(E-G-T(p)-Y-G) derived from Human CDK1/CDC2 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 34 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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