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Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody

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Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody
产品编号 TMAC-00786
别名 p-CDK1 (Thr14), p-CDK1 (T14), CDK1 (p-Thr14), CDK1 (p-T14)

Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-CDK1 (Thr14)。Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody 可用于 WB。

Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody

Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody
产品编号 TMAC-00786 别名 p-CDK1 (Thr14), p-CDK1 (T14), CDK1 (p-Thr14), CDK1 (p-T14)

Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-CDK1 (Thr14)。Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,245
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CDK1 (Thr14). Anti-Phospho-CDK1 (Thr14) Polyclonal Antibody can be used in WB.
别名p-CDK1 (Thr14), p-CDK1 (T14), CDK1 (p-Thr14), CDK1 (p-T14)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of extracts from HepG2 cells treated with Forskolin using Phospho-CDK1/CDC2 (Thr14) antibody TMAC-00786. The lane on the right is treated with the antigen-specific peptide.
应用
推荐剂量
WB: 1:500-1000
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Serine/threonine-protein kinase involved in the control of the cell cycle; essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Interacts with cyclins A, B1, B3, D, or E. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F transcriptional program and the initiation of DNA synthesis, and modulates G2 progression; controls the timing of entry into mitosis/meiosis by controlling the subsequent activation of cyclin B/CDK1 by phosphorylation, and coordinates the activation of cyclin B/CDK1 at the centrosome and in the nucleus.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phospho rylation site of threonine14(E-G-T(p)-Y-G) derived from Human CDK1/CDC2
抗原种属
human
Uniprot ID
化学信息
分子量Actual: 34 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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