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Anti-S100A9 Antibody (6Z270)

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Anti-S100A9 Antibody (6Z270)
产品编号 TMAY-01697
别名 S100 calcium binding protein A9, p14, MRP14, L1Ag, GAGB, Cagb, BEE22, AW546964, 60B8Ag

Anti-S100A9 Antibody (6Z270) 是一种 Rabbit 抗体,靶向 S100A9。Anti-S100A9 Antibody (6Z270) 可用于 IHC-P。

Anti-S100A9 Antibody (6Z270)

Anti-S100A9 Antibody (6Z270)

Rating icon 还可以
Anti-S100A9 Antibody (6Z270)
产品编号 TMAY-01697 别名 S100 calcium binding protein A9, p14, MRP14, L1Ag, GAGB, Cagb, BEE22, AW546964, 60B8Ag

Anti-S100A9 Antibody (6Z270) 是一种 Rabbit 抗体,靶向 S100A9。Anti-S100A9 Antibody (6Z270) 可用于 IHC-P。

规格价格库存数量
100 μL
¥ 2,294
5日内发货
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TargetMol 的所有产品仅用作科学研究或药证申报,不能被用于人体,我们不向个人提供产品和服务。请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
化合物带有盐酸盐离子、硫酸盐离子等是否和其本身有什么区别?盐形式和游离态有什么区别?
盐和非盐形式化合物的活性分子是一样的,在生物实验中起到的效果也一致,活性和使用方法都是一样的。只是由于呈盐不同,物理性质比如溶解度会有差异。建议您根据溶解、实验需求进行选择。
如何选择某个靶点的特异性或总的抑制剂?特异性和非特异性的区别是什么?
抑制剂按照特异性分为广谱 pan 和特异性 selective 两种。Pan 为某个靶点总的抑制剂,对所有亚型或整个家族的成员都有抑制作用。Selective 抑制剂针对某个蛋白激酶的某个亚型或家族中某个成员抑制率特别高或有特异性抑制作用。 一般评价一个抑制剂的抑制效率主要看 IC50 值,IC50 值越低,说明抑制剂效率越高。建议您根据以上几个特征进行综合选择,也可联系技术帮您推荐相关抑制剂。
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产品介绍

生物活性
产品描述
Anti-S100A9 Antibody (6Z270) is a Rabbit antibody targeting S100A9. Anti-S100A9 Antibody (6Z270) can be used in IHC-P.
别名S100 calcium binding protein A9, p14, MRP14, L1Ag, GAGB, Cagb, BEE22, AW546964, 60B8Ag
Ig Type
Rabbit IgG
克隆号
6Z270
交叉反应
Human
验证活性
Immunochemical staining of human S100A9 in human spleen with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
应用
推荐剂量
IHC-P: 1:100-1:500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human S100A9 (rh S100A9; TMPY-01357; NP_002956.1; Met1-Pro114).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. Protein S100-A9, also known as S100 calciumbinding protein A9, S100A9, and CAGB, is a member of the S-100 family. S100A9 is expressed by macrophages in acutely inflammed tissues and in chronic inflammation. It is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a calcium-binding protein. It has anti-microbial activity towards bacteria and fungi. The anti-microbial and proapoptotic activity of S100A9 is inhibited by zinc ions. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. S100A9 plays a role as a proinflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human S100A9 protein (TMPY-01357)
抗原种属
Human
研究领域
Calcium-binding Proteins and Related Molecules
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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